In utero exposure of rats to high-fat diets perturbs gene-expression profiles and cancer susceptibility of prepubertal mammary glands

Human studies suggest that high-fat diets (HFD) increase the risk of breast cancer. The 7,12 dimethylbenz[a]anthracene (DMBA)-induced mammary carcinogenesis rat model is commonly used to evaluate the effects of lifestyle factors such as HFD on mammary-tumor risk. Past studies focused primarily on th...

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Udgivet i:J Nutr Biochem
Main Authors: Govindarajah, Vinothini, Leung, Yuet-Kin, Ying, Jun, Gear, Robin, Bornschein, Robert L, Medvedovic, Mario, Ho, Shuk-Mei
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4761409/
https://ncbi.nlm.nih.gov/pubmed/26895667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jnutbio.2015.11.003
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