Pre-clinical evaluation of eight DOTA coupled gastrin-releasing peptide receptor (GRP-R) ligands for in vivo targeting of receptor-expressing tumors

BACKGROUND: Overexpression of the gastrin-releasing peptide receptor (GRP-R) has been documented in several human neoplasms such as breast, prostate, and ovarian cancer. There is growing interest in developing radiolabeled peptide-based ligands toward these receptors for the purpose of in vivo imagi...

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Bibliographische Detailangaben
Veröffentlicht in:EJNMMI Res
Hauptverfasser: Accardo, Antonella, Galli, Filippo, Mansi, Rosalba, Del Pozzo, Luigi, Aurilio, Michela, Morisco, Anna, Ringhieri, Paola, Signore, Alberto, Morelli, Giancarlo, Aloj, Luigi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Berlin Heidelberg 2016
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4761355/
https://ncbi.nlm.nih.gov/pubmed/26897133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-016-0175-x
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