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Constructing an integrated genetic and epigenetic cellular network for whole cellular mechanism using high-throughput next-generation sequencing data

BACKGROUND: Epigenetics has been investigated in cancer initiation, and development, especially, since the appearance of epigenomics. Epigenetics may be defined as the mechanisms that lead to heritable changes in gene function and without affecting the sequence of genome. These mechanisms explain ho...

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Detalles Bibliográficos
Publicado en:BMC Syst Biol
Main Authors: Chen, Bor-Sen, Li, Cheng-Wei
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4761210/
https://ncbi.nlm.nih.gov/pubmed/26897165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-016-0256-5
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