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The effects of sample size on population genomic analyses – implications for the tests of neutrality
BACKGROUND: One of the fundamental measures of molecular genetic variation is the Watterson’s estimator (θ), which is based on the number of segregating sites. The estimation of θ is unbiased only under neutrality and constant population growth. It is well known that the estimation of θ is biased wh...
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| Publicat a: | BMC Genomics |
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| Autor principal: | |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4761153/ https://ncbi.nlm.nih.gov/pubmed/26897757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2441-8 |
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