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Bidirectional crosstalk via IL‐6, PGE(2) and PGD(2) between murine myofibroblasts and alternatively activated macrophages enhances anti‐inflammatory phenotype in both cells

BACKGROUND AND PURPOSE: Alternatively activated macrophages (AAMs) are important cells in the resolution of inflammation and tissue repair. We examined the impact of myofibroblasts, a vital cell in wound healing and tissue repair, on the development and function of AAMs. EXPERIMENTAL APPROACH: The i...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Fernando, Maria R, Giembycz, Mark A, McKay, Derek M
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4761091/
https://ncbi.nlm.nih.gov/pubmed/26676587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13409
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