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Ligand and interfacial dynamics in a homodimeric hemoglobin

The structural dynamics of dimeric hemoglobin (HbI) from Scapharca inaequivalvis in different ligand-binding states is studied from atomistic simulations on the μs time scale. The intermediates are between the fully ligand-bound (R) and ligand-free (T) states. Tertiary structural changes, such as ro...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Struct Dyn
Hauptverfasser: Gupta, Prashant Kumar, Meuwly, Markus
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Crystallographic Association 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760971/
https://ncbi.nlm.nih.gov/pubmed/26958581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.4940228
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