Loss of the transcription factor Meis1 prevents sympathetic neurons target-field innervation and increases susceptibility to sudden cardiac death

Although cardio-vascular incidents and sudden cardiac death (SCD) are among the leading causes of premature death in the general population, the origins remain unidentified in many cases. Genome-wide association studies have identified Meis1 as a risk factor for SCD. We report that Meis1 inactivatio...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Bouilloux, Fabrice, Thireau, Jérôme, Ventéo, Stéphanie, Farah, Charlotte, Karam, Sarah, Dauvilliers, Yves, Valmier, Jean, Copeland, Neal G, Jenkins, Nancy A, Richard, Sylvain, Marmigère, Frédéric
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760953/
https://ncbi.nlm.nih.gov/pubmed/26857994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.11627
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