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Lentivirus-Mediated Knockdown of Astrocyte Elevated Gene-1 Inhibits Growth and Induces Apoptosis through MAPK Pathways in Human Retinoblastoma Cells

PURPOSE: To explore expression and function of astrocyte elevated gene-1 (AEG-1) in human retinoblastoma (RB). METHODS: The expression of AEG-1 in histological sections of human RBs and in RB cell lines was examined using immunohistochemical staining and RT-PCR and Western blotting respectively. We...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Chang, Ying, Li, Bin, Xu, Xiaolin, Shen, Ling, Bai, Haixia, Gao, Fei, Zhang, Zhibao, Jonas, Jost B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760765/
https://ncbi.nlm.nih.gov/pubmed/26894431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148763
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