Dichotomous roles for externalized cardiolipin in extracellular signaling: Promotion of phagocytosis and attenuation of innate immunity

Among the distinct molecular signatures present in the mitochondrion is the tetra-acylated anionic phospholipid cardiolipin, a lipid also present in primordial, single-cell bacterial ancestors of mitochondria and multiple bacterial species today. Cardiolipin is normally localized to the inner mitoch...

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Published in:Sci Signal
Main Authors: Balasubramanian, Krishnakumar, Maeda, Akihiro, Lee, Janet S., Mohammadyani, Dariush, Dar, Haider Hussain, Jiang, Jian Fei, St. Croix, Claudette M., Watkins, Simon, Tyurin, Vladimir A., Tyurina, Yulia Y., Klöditz, Katharina, Polimova, Anastassia, Kapralova, Valentyna I., Xiong, Zeyu, Ray, Prabir, Klein-Seetharaman, Judith, Mallampalli, Rama K., Bayir, Hülya, Fadeel, Bengt, Kagan, Valerian E.
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760701/
https://ncbi.nlm.nih.gov/pubmed/26396268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaa6179
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