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Nucleic acid reactivity : challenges for next-generation semiempirical quantum models

Semiempirical quantum models are routinely used to study mechanisms of RNA catalysis and phosphoryl transfer reactions using combined quantum mechanical/molecular mechanical methods. Herein, we provide a broad assessment of the performance of existing semiempirical quantum models to describe nucleic...

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Detalhes bibliográficos
Publicado no:J Comput Chem
Main Authors: Huang, Ming, Giese, Timothy J., York, Darrin M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760688/
https://ncbi.nlm.nih.gov/pubmed/25943338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcc.23933
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