Co-delivery of PLGA encapsulated invariant NKT cell agonist with antigenic protein induce strong T cell-mediated antitumor immune responses

Antitumor immunity can be enhanced by the coordinated release and delivery of antigens and immune-stimulating agents to antigen-presenting cells via biodegradable vaccine carriers. So far, encapsulation of TLR ligands and tumor-associated antigens augmented cytotoxic T cell (CTLs) responses. Here, w...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncoimmunology
Hauptverfasser: Dölen, Yusuf, Kreutz, Martin, Gileadi, Uzi, Tel, Jurjen, Vasaturo, Angela, van Dinther, Eric A. W., van Hout-Kuijer, Maaike A., Cerundolo, Vincenzo, Figdor, Carl G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2015
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760331/
https://ncbi.nlm.nih.gov/pubmed/26942088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1068493
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