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Endocardial-to-mesenchymal transformation and mesenchymal cell colonization at the onset of human cardiac valve development

The elucidation of mechanisms in semilunar valve development might enable the development of new therapies for congenital heart disorders. Here, we found differences in proliferation-associated genes and genes repressed by VEGF between human semilunar valve leaflets from first and second trimester h...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Monaghan, Michael G., Linneweh, Miriam, Liebscher, Simone, Van Handel, Ben, Layland, Shannon L., Schenke-Layland, Katja
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760315/
https://ncbi.nlm.nih.gov/pubmed/26674310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.133843
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