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All that glitters is not gold: the need to consider desirable and undesirable immune aspects of oncolytic virus therapy

Oncolytic viruses (OVs), a novel class of anticancer therapeutic agents, can overturn cancer-mediated immunosuppression and initiate antitumor immunity. Contrary to this paradigm, our recent study illustrates that oncolytic reovirus transiently augments cancer-associated immunosuppression immediatel...

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Foilsithe in:Oncoimmunology
Main Authors: Clements, Derek R, Kim, Youra, Gujar, Shashi A, Lee, Patrick WK
Formáid: Artigo
Teanga:Inglês
Foilsithe: Taylor & Francis 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760287/
https://ncbi.nlm.nih.gov/pubmed/26942069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1057674
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