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A light stabilizer (Tinuvin 770) that elutes from polypropylene plastic tubes is a potent L-type Ca(2+)-channel blocker.

A pharmacologically active agent was easily extracted by aqueous or organic solvents from laboratory plastic tubes (Falcon Blue Max) and has been chemically identified as bis(2,2,6,6-tetramethyl-4-piperidyl) sebacate. This compound (approximately 12 micrograms per tube approximately 25 nmol) blocked...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Glossmann, H, Hering, S, Savchenko, A, Berger, W, Friedrich, K, Garcia, M L, Goetz, M A, Liesch, J M, Zink, D L, Kaczorowski, G J
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1993
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47601/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8415734/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.20.9523
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