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Beyond hydroxyurea: new and old drugs in the pipeline for sickle cell disease

Despite Food and Drug Administration (FDA) approval of hydroxyurea to reduce the frequency of vaso-occlusive episodes, sickle cell disease (SCD) has continued to be treated primarily with analgesics for pain relief. However, elucidation of the multiple pathophysiologic mechanisms leading to vaso-occ...

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Detalhes bibliográficos
Publicado no:Blood
Autor principal: Telen, Marilyn J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760087/
https://ncbi.nlm.nih.gov/pubmed/26758919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-09-618553
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