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Interpreting change from patient reported outcome (PRO) endpoints: patient global ratings of concept versus patient global ratings of change, a case study among osteoporosis patients

BACKGROUND: Regulatory guidance recommends anchor-based methods for interpretation of treatment effects measured by PRO endpoints. Methodological pros and cons of patient global ratings of change vs. patient global ratings of concept have been discussed but empirical evidence in support of either ap...

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Detalhes bibliográficos
Publicado no:Health Qual Life Outcomes
Main Authors: Nixon, Annabel, Doll, Helen, Kerr, Cicely, Burge, Russel, Naegeli, April N.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4759933/
https://ncbi.nlm.nih.gov/pubmed/26896284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12955-016-0427-5
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