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Suicide Gene-Engineered Stromal Cells Reveal a Dynamic Regulation of Cancer Metastasis
Cancer-associated fibroblasts (CAFs) are a major cancer-promoting component in the tumor microenvironment (TME). The dynamic role of human CAFs in cancer progression has been ill-defined because human CAFs lack a unique marker needed for a cell-specific, promoter-driven knockout model. Here, we deve...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4759812/ https://ncbi.nlm.nih.gov/pubmed/26893143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21239 |
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