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A physiome interoperability roadmap for personalized drug development

The goal of developing therapies and dosage regimes for characterized subgroups of the general population can be facilitated by the use of simulation models able to incorporate information about inter-individual variability in drug disposition (pharmacokinetics), toxicity and response effect (pharma...

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Publicat a:Interface Focus
Autors principals: Thomas, Simon, Wolstencroft, Katherine, de Bono, Bernard, Hunter, Peter J.
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4759752/
https://ncbi.nlm.nih.gov/pubmed/27051513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsfs.2015.0094
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