An 8-gene mRNA expression profile in circulating tumor cells predicts response to aromatase inhibitors in metastatic breast cancer patients

BACKGROUND: Molecular characterization of circulating tumor cells (CTC) is promising for personalized medicine. We aimed to identify a CTC gene expression profile predicting outcome to first-line aromatase inhibitors in metastatic breast cancer (MBC) patients. Methods: CTCs were isolated from 78 MBC...

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Publicado en:BMC Cancer
Main Authors: Reijm, Esther A., Sieuwerts, Anieta M., Smid, Marcel, Vries, Joan Bolt-de, Mostert, Bianca, Onstenk, Wendy, Peeters, Dieter, Dirix, Luc Y., Seynaeve, Caroline M., Jager, Agnes, de Jongh, Felix E., Hamberg, Paul, van Galen, Anne, Kraan, Jaco, Jansen, Maurice P. H. M., Gratama, Jan W., Foekens, John A., Martens, John W. M., Berns, Els M. J. J., Sleijfer, Stefan
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2016
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4759736/
https://ncbi.nlm.nih.gov/pubmed/26892682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2155-y
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