Combined Secretomics and Transcriptomics Revealed Cancer-Derived GDF15 is Involved in Diffuse-Type Gastric Cancer Progression and Fibroblast Activation

Gastric cancer is classified into two subtypes, diffuse and intestinal. The diffuse-type gastric cancer (DGC) has poorer prognosis, and the molecular pathology is not yet fully understood. The purpose of this study was to identify functional secreted molecules involved in DGC progression. We integra...

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Publicat a:Sci Rep
Autors principals: Ishige, Takayuki, Nishimura, Motoi, Satoh, Mamoru, Fujimoto, Mai, Fukuyo, Masaki, Semba, Toshihisa, Kado, Sayaka, Tsuchida, Sachio, Sawai, Setsu, Matsushita, Kazuyuki, Togawa, Akira, Matsubara, Hisahiro, Kaneda, Atsushi, Nomura, Fumio
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4759594/
https://ncbi.nlm.nih.gov/pubmed/26892343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21681
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