Ultrasensitivity in the Cofilin Signaling Module: A Mechanism for Tuning T Cell Responses

Ultrasensitivity allows filtering weak activating signals and responding emphatically to small changes in stronger stimuli. In the presence of positive feedback loops, ultrasensitivity enables the existence of bistability, which convert graded stimuli into switch-like, sometimes irreversible, respon...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Ramirez-Munoz, Rocio, Castro-Sánchez, Patricia, Roda-Navarro, Pedro
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2016
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4759566/
https://ncbi.nlm.nih.gov/pubmed/26925064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00059
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