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Pronuclear removal of tripronuclear zygotes can establish heteroparental normal karyotypic human embryonic stem cells

PURPOSE: This study aimed to derive heteroparental normal karyotypic human embryonic stem cells (hESCs) from microsurgically corrected tripronuclear (3PN) zygotes. METHODS: After sequential culture for 5–6 days, embryos developed from microsurgically corrected 3PN zygotes were analyzed by fluorescen...

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Detalhes bibliográficos
Publicado no:J Assist Reprod Genet
Main Authors: Liao, Hong-Qing, OuYang, Qi, Zhang, Shuo-Ping, Cheng, De-Hua, Lu, Guang-Xiu, Lin, Ge
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4759007/
https://ncbi.nlm.nih.gov/pubmed/26727933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-015-0634-8
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