Endothelial Cell Bioenergetics and Mitochondrial DNA Damage Differ in Humans Having African or West Eurasian Maternal Ancestry

BACKGROUND: We hypothesized that endothelial cells having distinct mitochondrial genetic backgrounds would show variation in mitochondrial function and oxidative stress markers concordant with known differential cardiovascular disease susceptibilities. To test this hypothesis, mitochondrial bioenerg...

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Detalhes bibliográficos
Publicado no:Circ Cardiovasc Genet
Main Authors: Krzywanski, David M., Moellering, Douglas R., Westbrook, David G., Dunham-Snary, Kimberly J., Brown, Jamelle, Bray, Alexander W., Feeley, Kyle P., Sammy, Melissa J., Smith, Matthew R., Schurr, Theodore G., Vita, Joseph A., Ambalavanan, Namasivayam, Calhoun, David, Dell’Italia, Louis, Ballinger, Scott W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4758889/
https://ncbi.nlm.nih.gov/pubmed/26787433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.115.001308
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