Protective effect of fucoidan from Fucus vesiculosus on liver fibrosis via the TGF-β1/Smad pathway-mediated inhibition of extracellular matrix and autophagy

Liver fibrosis is a dynamic reversible pathological process in the development of chronic liver disease to cirrhosis. However, the current treatments are not administered for a long term due to their various side effects. Autophagy is initiated to decompose damaged or excess organelles, which had be...

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Bibliografiske detaljer
Udgivet i:Drug Des Devel Ther
Main Authors: Li, Jingjing, Chen, Kan, Li, Sainan, Feng, Jiao, Liu, Tong, Wang, Fan, Zhang, Rong, Xu, Shizan, Zhou, Yuqing, Zhou, Shunfeng, Xia, Yujing, Lu, Jie, Zhou, Yingqun, Guo, Chuanyong
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2016
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4758785/
https://ncbi.nlm.nih.gov/pubmed/26929597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S98740
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