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Ivabradine Prevents Low Shear Stress Induced Endothelial Inflammation and Oxidative Stress via mTOR/eNOS Pathway

Ivabradine not only reduces heart rate but has other cardiac and vascular protective effects including anti-inflammation and anti-oxidation. Since endothelial nitric oxide synthase (eNOS) is a crucial enzyme in maintaining endothelial activity, we aimed to investigate the impact of ivabradine in low...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Li, Bing, Zhang, Junxia, Wang, Zhimei, Chen, Shaoliang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4758626/
https://ncbi.nlm.nih.gov/pubmed/26890696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149694
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