APOE ɛ2 is associated with white matter hyperintensity volume in CADASIL

Apolipoprotein E (APOE) increases the risk for Alzheimer’s disease (ɛ4 allele) and cerebral amyloid angiopathy (ɛ2 and ɛ4), but its role in small vessel disease (SVD) is debated. Here we studied the effects of APOE on white matter hyperintensity volume (WMHV) in CADASIL (cerebral autosomal dominant...

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Publicat a:J Cereb Blood Flow Metab
Autors principals: Gesierich, Benno, Opherk, Christian, Rosand, Jonathan, Gonik, Mariya, Malik, Rainer, Jouvent, Eric, Hervé, Dominique, Adib-Samii, Poneh, Bevan, Steve, Pianese, Luigi, Silvestri, Serena, Dotti, Maria T, De Stefano, Nicola, van der Grond, Jeroen, Boon, Elles M J, Pescini, Francesca, Rost, Natalia, Pantoni, Leonardo, Lesnik Oberstein, Saskia A, Federico, Antonio, Ragno, Michele, Markus, Hugh S, Tournier-Lasserve, Elisabeth, Chabriat, Hugues, Dichgans, Martin, Duering, Marco, Ewers, Michael
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publications 2016
Matèries:
Brief Communication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4758562/
https://ncbi.nlm.nih.gov/pubmed/25920955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2015.85
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