Differential Role of a NF-kappaB Transcriptional Response Element in Endothelial versus Intimal Cell VCAM-1 Expression

RATIONALE: Human and murine Vcam1 promoters contain 2 adjacent NF-κB-binding elements. Both are essential for cytokine-induced transcription of transiently transfected promoter-reporter constructs. However, the relevance of these insights to regulation of the endogenous Vcam1 gene and to pathophysio...

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Pubblicato in:Circ Res
Autori principali: Milstone, David S., Ilyama, Motoi, Chen, Mian, O’Donnell, Peter, Davis, Vannessa M., Plutzky, Jorge, Brown, Jonathan D., Haldar, Saptarsi M., Siu, Allan, Lau, Andrew C., Zhu, Su-Ning, Basheer, Mayada F., Collins, Tucker, Jongstra-Bilen, Jenny, Cybulsky, Myron I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4758452/
https://ncbi.nlm.nih.gov/pubmed/26034041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.117.306666
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