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Synthetically Modified Viral Capsids as Versatile Carriers for Use in Antibody-Based Cell Targeting

The present study describes an efficient and reliable method for the preparation of MS2 viral capsids that are synthetically modified with antibodies using a rapid oxidative coupling strategy. The overall protocol delivers conjugates in high yields and recoveries, requires a minimal excess of antibo...

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Detalhes bibliográficos
Publicado no:Bioconjug Chem
Main Authors: ElSohly, Adel M., Netirojjanakul, Chawita, Aanei, Ioana L., Jager, Astraea, Bendall, Sean C., Farkas, Michelle E., Nolan, Garry P., Francis, Matthew B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4758138/
https://ncbi.nlm.nih.gov/pubmed/26076186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.5b00226
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