Circulating insulin-like growth factor-I, insulin-like growth factor binding protein-3 and terminal duct lobular unit involution of the breast: a cross-sectional study of women with benign breast disease

BACKGROUND: Terminal duct lobular units (TDLUs) are the primary structures from which breast cancers and their precursors arise. Decreased age-related TDLU involution and elevated mammographic density are both correlated and independently associated with increased breast cancer risk, suggesting that...

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Published in:Breast Cancer Res
Main Authors: Horne, Hisani N., Sherman, Mark E., Pfeiffer, Ruth M., Figueroa, Jonine D., Khodr, Zeina G., Falk, Roni T., Pollak, Michael, Patel, Deesha A., Palakal, Maya M., Linville, Laura, Papathomas, Daphne, Geller, Berta, Vacek, Pamela M., Weaver, Donald L., Chicoine, Rachael, Shepherd, John, Mahmoudzadeh, Amir Pasha, Wang, Jeff, Fan, Bo, Malkov, Serghei, Herschorn, Sally, Hewitt, Stephen M., Brinton, Louise A., Gierach, Gretchen L.
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4758090/
https://ncbi.nlm.nih.gov/pubmed/26893016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-016-0678-4
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