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Impact of Longevity Interventions on a Validated Mouse Clinical Frailty Index

This article investigates the effect on the mouse frailty index (FI), of factors known to influence lifespan and healthspan in mice: strain (short-lived DBA/2J mice vs long-lived C57BL/6J mice), calorie restriction (CR), and resveratrol treatment. The mouse FI, based on deficit accumulation, was rec...

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Detalles Bibliográficos
Publicado en:J Gerontol A Biol Sci Med Sci
Main Authors: Kane, Alice E., Hilmer, Sarah N., Boyer, Dawn, Gavin, Kristan, Nines, Dawn, Howlett, Susan E., de Cabo, Rafael, Mitchell, Sarah J.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4757961/
https://ncbi.nlm.nih.gov/pubmed/25711530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glu315
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