GRHL2-miR-200-ZEB1 maintains the epithelial status of ovarian cancer through transcriptional regulation and histone modification

Epithelial-mesenchymal transition (EMT), a biological process by which polarized epithelial cells convert into a mesenchymal phenotype, has been implicated to contribute to the molecular heterogeneity of epithelial ovarian cancer (EOC). Here we report that a transcription factor—Grainyhead-like 2 (G...

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Publicat a:Sci Rep
Autors principals: Chung, Vin Yee, Tan, Tuan Zea, Tan, Ming, Wong, Meng Kang, Kuay, Kuee Theng, Yang, Zhe, Ye, Jieru, Muller, Julius, Koh, Cheryl M., Guccione, Ernesto, Thiery, Jean Paul, Huang, Ruby Yun-Ju
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4757891/
https://ncbi.nlm.nih.gov/pubmed/26887977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19943
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