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Peripheral lymphoid volume expansion and maintenance are controlled by gut microbiota via RALDH(+) dendritic cells

Lymphocyte homing to draining lymph nodes is critical for the initiation of immune responses. Secondary lymphoid organs of germ-free mice are underdeveloped. How gut commensal microbes remotely regulate cellularity and volume of secondary lymphoid organs remains unknown. We report here that driven b...

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Detalhes bibliográficos
Publicado no:Immunity
Main Authors: Zhang, Zongde, Li, Jianjian, Zheng, Wencheng, Zhao, Guang, Zhang, Hong, Wang, Xiaofei, Guo, Yaqian, Qin, Chuan, Shi, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4757854/
https://ncbi.nlm.nih.gov/pubmed/26885858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2016.01.004
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