Myelination-related genes are associated with decreased white matter integrity in schizophrenia

Disruptions in white matter (WM) tract structures have been implicated consistently in the pathophysiology of schizophrenia. Global WM integrity – as measured by fractional anisotropy (FA) – is highly heritable and may provide a good endophenotype for genetic studies of schizophrenia. WM abnormaliti...

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Published in:Eur J Hum Genet
Main Authors: Chavarria-Siles, Ivan, White, Tonya, de Leeuw, Christiaan, Goudriaan, Andrea, Lips, Esther, Ehrlich, Stefan, Turner, Jessica A, Calhoun, Vince D, Gollub, Randy L, Magnotta, Vincent A, Ho, Beng-Choon, Smit, August B, Verheijen, Mark HG, Posthuma, Danielle
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4757770/
https://ncbi.nlm.nih.gov/pubmed/26014434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2015.120
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