Hydroxytyrosol Protects against Myocardial Ischemia/Reperfusion Injury through a PI3K/Akt-Dependent Mechanism

Objective. To investigate the effects and mechanisms of hydroxytyrosol (HT) during the pathogenesis of myocardial ischemia reperfusion (I/R) in rat hearts. Methods. The rats were randomized into five groups: sham group, I/R group, HT+I/R group, HT+LY294002+I/R group, and LY+I/R group. Myocardial inf...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Pei, Ying-hao, Chen, Jiao, Xie, Liang, Cai, Xiao-min, Yang, Run-Hua, Wang, Xing, Gong, Jian-bin
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4757717/
https://ncbi.nlm.nih.gov/pubmed/26966340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/1232103
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