The Mutational Landscape of Acute Promyelocytic Leukemia Reveals an Interacting Network of Co-Occurrences and Recurrent Mutations

Preliminary Acute Promyelocytic Leukemia (APL) whole exome sequencing (WES) studies have identified a huge number of somatic mutations affecting more than a hundred different genes mainly in a non-recurrent manner, suggesting that APL is a heterogeneous disease with secondary relevant changes not ye...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Ibáñez, Mariam, Carbonell-Caballero, José, García-Alonso, Luz, Such, Esperanza, Jiménez-Almazán, Jorge, Vidal, Enrique, Barragán, Eva, López-Pavía, María, LLop, Marta, Martín, Iván, Gómez-Seguí, Inés, Montesinos, Pau, Sanz, Miguel A., Dopazo, Joaquín, Cervera, José
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4757557/
https://ncbi.nlm.nih.gov/pubmed/26886259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148346
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