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Effects of Clonidine on Breathing during Sleep and Susceptibility to Central Apnoea
We hypothesized that administration of clonidine would decrease the hypocapnic apnoeic threshold (HAT) and widen the CO(2) reserve during non-REM sleep. METHODS: Ten healthy subjects (4 females) (age 22.3±3.0 years; BMI 25.5±3.4 kg/m(2)) were randomized to receive placebo or 0.1 mg/45Kg of clonidine...
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| Publicado no: | Respir Physiol Neurobiol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4757488/ https://ncbi.nlm.nih.gov/pubmed/23017329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.resp.2012.09.005 |
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