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Exocytotic fusion pores are composed of both lipids and proteins

During exocytosis, fusion pores form the first aqueous connection that allows escape of neurotransmitters and hormones from secretory vesicles. Although it is well established that SNARE proteins catalyze fusion, the structure and composition of fusion pores remain unknown. Here, we exploited the ri...

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Detalhes bibliográficos
Publicado no:Nat Struct Mol Biol
Main Authors: Bao, Huan, Goldschen-Ohm, Marcel, Jeggle, Pia, Chanda, Baron, Edwardson, J Michael, Chapman, Edwin R
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4756907/
https://ncbi.nlm.nih.gov/pubmed/26656855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3141
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