Genome-wide profiling of nucleosome sensitivity and chromatin accessibility in Drosophila melanogaster

Nucleosomal DNA is thought to be generally inaccessible to DNA-binding factors, such as micrococcal nuclease (MNase). Here, we digest Drosophila chromatin with high and low concentrations of MNase to reveal two distinct nucleosome types: MNase-sensitive and MNase-resistant. MNase-resistant nucleosom...

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Библиографические подробности
Опубликовано в: :Nucleic Acids Res
Главные авторы: Chereji, Răzvan V., Kan, Tsung-Wai, Grudniewska, Magda K., Romashchenko, Alexander V., Berezikov, Eugene, Zhimulev, Igor F., Guryev, Victor, Morozov, Alexandre V., Moshkin, Yuri M.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2016
Предметы:
Gene regulation, Chromatin and Epigenetics
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4756854/
https://ncbi.nlm.nih.gov/pubmed/26429969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv978
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