Binding of transcription factor GabR to DNA requires recognition of DNA shape at a location distinct from its cognate binding site

Mechanisms for transcription factor recognition of specific DNA base sequences are well characterized and recent studies demonstrate that the shape of these cognate binding sites is also important. Here, we uncover a new mechanism where the transcription factor GabR simultaneously recognizes two cog...

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Udgivet i:Nucleic Acids Res
Main Authors: Al-Zyoud, Walid A., Hynson, Robert MG., Ganuelas, Lorraine A., Coster, Adelle CF., Duff, Anthony P., Baker, Matthew AB., Stewart, Alastair G., Giannoulatou, Eleni, Ho, Joshua WK., Gaus, Katharina, Liu, Dali, Lee, Lawrence K., Böcking, Till
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
Fag:
Structural Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4756830/
https://ncbi.nlm.nih.gov/pubmed/26681693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1466
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