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ECM microenvironment unlocks brown adipogenic potential of adult human bone marrow-derived MSCs

Key to realizing the diagnostic and therapeutic potential of human brown/brite adipocytes is the identification of a renewable, easily accessible and safe tissue source of progenitor cells, and an efficacious in vitro differentiation protocol. We show that macromolecular crowding (MMC) facilitates b...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lee, Michelle H., Goralczyk, Anna G., Kriszt, Rókus, Ang, Xiu Min, Badowski, Cedric, Li, Ying, Summers, Scott A., Toh, Sue-Anne, Yassin, M. Shabeer, Shabbir, Asim, Sheppard, Allan, Raghunath, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4756694/
https://ncbi.nlm.nih.gov/pubmed/26883894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21173
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