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Dose- and time-dependent effects of actomyosin inhibition on live mouse outflow resistance and aqueous drainage tissues
Actomyosin contractility modulates outflow resistance of the aqueous drainage tissues and intraocular pressure, a key pathogenic factor of glaucoma. We established methodology to reliably analyze the effect of latrunculin-B (Lat-B)-induced actin depolymerization on outflow physiology in live mice. A...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4756686/ https://ncbi.nlm.nih.gov/pubmed/26884319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21492 |
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