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A web-oriented software for the optimization of pooled experiments in NGS for detection of rare mutations

BACKGROUND: The cost per patient of next generation sequencing for detection of rare mutations may be significantly reduced using pooled experiments. Recently, some techniques have been proposed for the planning of pooled experiments and for the optimal allocation of patients into pools. However, th...

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Bibliografski detalji
Izdano u:BMC Res Notes
Glavni autori: Evangelista, Daniela, Zuccaro, Antonio, Lančinskas, Algirdas, Žilinskas, Julius, Guarracino, Mario R.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4756526/
https://ncbi.nlm.nih.gov/pubmed/26888663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13104-016-1889-6
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