Novel synthetic benzimidazole-derived oligosaccharide, M3BIM, prevents ex vivo platelet aggregation and in vivo thromboembolism

BACKGROUND: Thrombus formation, a phenomenon primarily related to increased platelet activation, plays a key role in cardiovascular and cerebrovascular diseases. Although the established antiplatelet agents, such as aspirin and clopidogrel, have been shown to be beneficial in treating thromboembolic...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:J Biomed Sci
Autori principali: Yen, Ting-Lin, Wu, Ming-Ping, Chung, Chi-Li, Yang, Wen-Bin, Jayakumar, Thanasekaran, Geraldine, Pitchairaj, Chou, Chih-Ming, Chang, Chia-Yau, Lu, Wan-Jung, Sheu, Joen-Rong
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4756413/
https://ncbi.nlm.nih.gov/pubmed/26887315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-016-0245-4
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