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Design and rationale of the ATHENA study – A 12-month, multicentre, prospective study evaluating the outcomes of a de novo everolimus-based regimen in combination with reduced cyclosporine or tacrolimus versus a standard regimen in kidney transplant patients: study protocol for a randomised controlled trial

BACKGROUND: Immunosuppression with calcineurin inhibitors remains the mainstay of treatment after kidney transplantation; however, long-term use of these drugs may be associated with nephrotoxicity. In this regard, the current approach is to optimise available immunosuppressive regimens to reduce th...

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發表在:Trials
Main Authors: Sommerer, Claudia, Suwelack, Barbara, Dragun, Duska, Schenker, Peter, Hauser, Ingeborg A., Nashan, Björn, Thaiss, Friedrich
格式: Artigo
語言:Inglês
出版: BioMed Central 2016
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4756406/
https://ncbi.nlm.nih.gov/pubmed/26888217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-016-1220-9
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