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Optimized Blanching Reduces the Host Cell Protein Content and Substantially Enhances the Recovery and Stability of Two Plant-Derived Malaria Vaccine Candidates

Plants provide an advantageous expression platform for biopharmaceutical proteins because of their low pathogen burden and potential for inexpensive, large-scale production. However, the purification of target proteins can be challenging due to issues with extraction, the removal of host cell protei...

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Detaylı Bibliyografya
Yayımlandı:Front Plant Sci
Asıl Yazarlar: Menzel, Stephan, Holland, Tanja, Boes, Alexander, Spiegel, Holger, Bolzenius, Johanna, Fischer, Rainer, Buyel, Johannes F.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4756251/
https://ncbi.nlm.nih.gov/pubmed/26925077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpls.2016.00159
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