Posttranslational processing of FGF23 in osteocytes during the osteoblast to osteocyte transition

FGF23 is an O-glycosylated circulating peptide hormone with a critical role in phosphate homeostasis; it is inactivated by cellular proprotein convertases in a pre-release degradative pathway. We have here examined the metabolism of FGF23 in a model bone cell line, IDG-SW3, prior to and following di...

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Veröffentlicht in:Bone
Hauptverfasser: Yamamoto, Hiroyuki, Ramos-Molina, Bruno, Lick, Adam N., Prideaux, Matthew, Albornoz, Valeria, Bonewald, Lynda, Lindberg, Iris
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755901/
https://ncbi.nlm.nih.gov/pubmed/26746780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2015.12.055
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