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A Septin Requirement Differentiates Autonomous- and Contact-Facilitated T Cell Proliferation

T cell proliferation is initiated by T cell antigen receptor (TCR) triggering and/or by soluble growth factors. In characterizing T cells lacking the septin cytoskeleton, we found that successful cell division has discrete septin-dependent and -independent pathways. Septin-deficient T cells failed c...

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Détails bibliographiques
Publié dans:Nat Immunol
Auteurs principaux: Mujal, Adriana M., Gilden, Julia K., Gérard, Audrey, Kinoshita, Makoto, Krummel, Matthew F.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755847/
https://ncbi.nlm.nih.gov/pubmed/26692174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3330
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