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CD200 increases alternatively activated macrophages through CREB - C/EBP-beta signaling

The concept of macrophage polarization toward different phenotypes after CNS injury has been increasingly discussed. Here, we propose that CD200 treatment may help shift pro-inflammatory macrophages to an Arg1-, TGM2- and TGF-β-positive phenotype. Rat macrophages were stimulated by IFN-γ and LPS to...

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Publicado en:J Neurochem
Autores principales: Hayakawa, Kazuhide, Wang, Xiaohua, Lo, Eng H.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755817/
https://ncbi.nlm.nih.gov/pubmed/26670206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13492
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