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Risk based In Vitro Performance Assessment of Extended Release Abuse Deterrent Formulations

High strength extended release opioid products, which are indispensable tools in the management of pain, are associated with serious risks of unintentional and potentially fatal overdose, as well as of misuse and abuse that might lead to addiction. The issue of drug abuse becomes increasingly promin...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Pharm
Hauptverfasser: Xu, Xiaoming, Gupta, Abhay, Al-Ghabeish, Manar, Calderon, Silvia N., Khan, Mansoor A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755808/
https://ncbi.nlm.nih.gov/pubmed/26784976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2016.01.031
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