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A mathematical model explains saturating axon guidance responses to molecular gradients

Correct wiring is crucial for the proper functioning of the nervous system. Molecular gradients provide critical signals to guide growth cones, which are the motile tips of developing axons, to their targets. However, in vitro, growth cones trace highly stochastic trajectories, and exactly how molec...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Nguyen, Huyen, Dayan, Peter, Pujic, Zac, Cooper-White, Justin, Goodhill, Geoffrey J
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755759/
https://ncbi.nlm.nih.gov/pubmed/26830461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.12248
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